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The purpose of this study was to examine the profound effects of the amino acid linkers on the melanoma-targeting and pharmacokinetic properties of (111)In-labeled lactam bridge-cyclized DOTA-[X]-CycMSH(hex) {1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-[X]-c[Asp-His-dPhe-Arg-Trp-Lys]-CONH(2); X = GGNle, GENle, or NleGE; GG = -Gly-Gly- and GE = -Gly-Glu-} peptides.

the journal of nuclear medicine

Effects of the Amino Acid Linkers on the Melanoma-Targeting and Pharmacokinetic Properties of <sup>111</sup>In-Labeled Lactam Bridge–Cyclized α-MSH Peptides

Effects of the Amino Acid Linkers on the Melanoma-Targeting and Pharmacokinetic Properties of 111In-Labeled Lactam Bridge–Cyclized α-MSH Peptides

Effects of the Amino Acid Linkers on the Melanoma-Targeting and Pharmacokinetic Properties of ¹¹¹In-Labeled Lactam Bridge–Cyclized α-MSH Peptides