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Abraxane (nanoparticle albumin-bound paclitaxel) is an anticancer drug approved by the Food and Drug Administration. However, the mechanism of action of Abraxane is complex, and no established biomarker is available to accurately monitor its treatment outcomes. The aim of this study was to investigate whether the integrin-specific PET tracer 18F-FPPRGD2 (investigational new drug 104150) can be used to monitor early response of tumors to Abraxane therapy.

18F-FPPRGD2 and 18F-FDG PET of Response to Abraxane Therapy

¹⁸F-FPPRGD2 and ¹⁸F-FDG PET of Response to Abraxane Therapy