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The PET tracer (11)C-(R)-PK11195 (PK) is an antagonist of the peripheral-type benzodiazepine binding site and allows the noninvasive imaging of microglial activation seen in several neurologic disorders affecting the mature and developing brain. The objective of this study was to derive the biodistribution and in vivo radiation dose estimates of PK in children studied for brain inflammatory conditions and in healthy adults.

PET-Derived Biodistribution and Dosimetry of the Benzodiazepine Receptor-Binding Radioligand 11C-(R)-PK11195 in Children and Adults

PET-Derived Biodistribution and Dosimetry of the Benzodiazepine Receptor-Binding Radioligand ¹¹C-(R)-PK11195 in Children and Adults