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Because of the recent development of an iodopyridopyrimidinone Abl protein kinase inhibitor (PKI), (124)I-SKI-212230 ((124)I-SKI230), we investigated the feasibility of a PET-based molecular imaging method for the direct visualization of Abl kinase expression and PKI treatment.

124I-Iodopyridopyrimidinone for PET of Abl Kinase–Expressing Tumors In Vivo

¹²⁴I-Iodopyridopyrimidinone for PET of Abl Kinase–Expressing Tumors In Vivo