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Sequential testing by coronary CT angiography (CTA) and myocardial perfusion SPECT (MPS) obtained on stand-alone scanners may be needed to diagnose coronary artery disease in equivocal cases. We have developed an automated technique for MPS-CTA registration and demonstrate its utility for improved MPS quantification by guiding the coregistered physiologic (MPS) with anatomic CTA information.

Quantitative Analysis of Myocardial Perfusion SPECT Anatomically Guided by Coregistered 64-Slice Coronary CT Angiography