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(123)I-Iomazenil brain SPECT has been used for the detection of epileptogenic foci, especially when surgical intervention is considered. Although epileptogenic foci exhibit a decrease in (123)I-iomazenil accumulation, normal cerebral cortices often exhibit similar findings because of thin cortical ribbons, gray matter atrophy, or pathologic brain structures. In the present study, we created (123)I-iomazenil SPECT images corrected for gray matter volume using MRI and tested whether the detectability of the epileptogenic foci improved.

the journal of nuclear medicine

MRI-Based Correction for Partial-Volume Effect Improves Detectability of Intractable Epileptogenic Foci on <sup>123</sup>I-Iomazenil Brain SPECT Images

MRI-Based Correction for Partial-Volume Effect Improves Detectability of Intractable Epileptogenic Foci on 123I-Iomazenil Brain SPECT Images

MRI-Based Correction for Partial-Volume Effect Improves Detectability of Intractable Epileptogenic Foci on ¹²³I-Iomazenil Brain SPECT Images