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The purposes of this study were to characterize the performance of a 3-dimensional (3D) ordered-subset expectation maximization (OSEM) algorithm in the quantification of left ventricular (LV) function with (99m)Tc-labeled agent gated SPECT (G-SPECT), the QGS program, and a beating-heart phantom and to optimize the reconstruction parameters for clinical applications.

journal of nuclear medicine technology

Three-Dimensional Ordered-Subset Expectation Maximization Iterative Protocol for Evaluation of Left Ventricular Volumes and Function by Quantitative Gated SPECT: A Dynamic Phantom Study