Blood HCV dynamic phase by Amplicor HCV monitor v2.0 ( the high range method ) for the high-dense region measurement. The identification of virological refractoriness example in the phase I. The examination in the administration in PEG-IFN.ALPHA.-2b/IFN.ALPHA.-2b+ ribavirin combined use 48 weeks for chronic hepatitis C of high HCV quantity and HCV genotype 1b.