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Cite as: Ondenge K, Khalil G, Odero I, Ford DC, Thompson WW, Awuonda E, Omoro T, Gust DA. Factors associated with psychological distress among members of HIV discordant couples in western Kenya: the role of adverse childhood experiences. J Glob Health Rep 2018; 2: e2018018. Background The relationship between measures of psychological distress and factors such as adverse childhood experiences (ACE) and HIV infection have not been well studied among members of HIV discordant couples living in Kenya.