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Silica-bonded S-sulfonic acid (SBSSA) was used as a re- cyclable and reusable catalyst for the synthesis of β-amino alcohols. Several amines were reacted with epoxides to afford regioselective β-amino alcohols in high yield under solvent-free conditions at room temperature.

Regioselective Ring Opening of Epoxides with Amines Using Silica-bonded S-sulfonic Acid under Solvent-free Conditions