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Background: Although there are a number of publications dem-onstratinghow depression increases cardiovascular morbidity and mortality, thereare few and contradictory publications regarding heart ratefluctuations and late potentials. In the present study, we aimed toinvestigate whether heart rate fluctuations (HRF) and late ventricularpotential values are different in patients with depression compared tothose in normal individuals. Methods: Thirty two untreated depressivepatients having no associated clinical cardiovascular disease and 29healthy individuals were recruited in the study. Beck′sdepression inventory was used to determine patients with depression.Recordings were made with the Cardioscan digital ECG halter recorder.Heart rate fluctuations and late potential criteria were evaluatedusing a computer with Cardioscan software. Results: There was adecrease in standard deviation of normal to normal intervals and itsindex (p= 0.001) and an increase in sympathetic tonus (p= 0.006) indepressive patients. No statistical significance in regard to the lateventricular potential values was determined between depressive patientsand healthy individuals. Conclusions: There was a decrease in some ofthe HRF parameters and an increase in sympathetic tonus in depressivepatients, but late ventricular potentials were not different from thoseof healthy individuals.

Heart Rate Fluctuations and Late Ventricular Potentials in Depression Patients without Clinical Cardiovascular disease