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The disease which reportedly began in Chinese city Wuhan in November-December 2019 manifesting as severe respiratory illness, soon spread to various parts of the world, and was named COVID-19, and declared a pandemic disease by the World Health Organization (WHO). The disease further spread to certain Arabian and European countries. While these countries were recovering from the epidemic, the disease took hold in the UK and USA, and the South American, Arabian, and South Asian countries, predominantly affecting Brazil, Peru, Iran, and India. Presently, most of the European countries are witnessing recurrent outbreaks and a resurgence of COVID-19, whereas the epidemic is not yet over in other countries [1]. This calls for a need for exploring further the factors affecting the disease transmission, pathogenicity, and immunogenicity, apart from rigorous preventive and control measures, and vigorous vigilance and surveillance.

Exploring COVID-19: Relating the spike protein to infectivity, pathogenicity and Immunogenicity