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Copyright© 2018, ASP Ins. This open-access article is published under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License which permits Share (copy and redistribute the material in any medium or format) and Adapt (remix, transform, and build upon the material) under the Attribution-NonCommercial terms. [1] Effects of huangqi jianzhong tang on hematological and biochemical parameters in judo athletes [2] The effects of graded resistance exercise on platelet aggregation and activation [3] Responses of platelet activation and function to a single bout of resistance exercise and recovery [4] Can white blood cell activation be one of the major factors that affect hemorheological parameters during and after exercise? [5] Ageing: Physiological aspects [6] Exercise and aging [7] Effects of exercise intensity and duration on fat metabolism in trained and untrained older males [8] Differential effects of aging on limb blood flow in humans [9] Endothelial dysfunction and aging: An update [10] Sports as a cause of oxidative stress and hemolysis [11] Sports haematology [12] Exercise-induced oxidative stress leads hemolysis in sedentary but not trained humans [13] Hemorheological changes during human aging [14] Blood viscosity and aging [15] Study on the hemorheological parameters of oldest-old residents in the East-Hungarian city, Debrecen [16] Leukocyte activation, erythrocyte damage, lipid profile and oxidative stress imposed by high competition physical exercise in adolescents [17] Gender differences in exercise–induced intravascular haemolysis during race training in thoroughbred horses [18] The acute effects of resistance exercise on the main determinants of blood rheology [19] Effects of resistance exercise intensity on the main Determinants of blood rheology [20] Exercise hemorheology as a three acts play with metabolic actors: Is it of clinical relevance? [21] Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration [22] Endothelium, aging, and hypertension [23] Arterial stiffness, physical activity, and atrial natriuretic Peptide gene polymorph-ism in older subjects [24] Effects of exercise on rheological and microcirculatory parameters [25] Postexercise red cell aggregation is negatively correlated with blood lactate rate of disappearance [26] Changes in blood haemorheological parameters after submaximal exercise in trained and untrained subjects [27] Footstrike is the major cause of hemolysis during running [28] The hemolysis kinetics of psoriatic red blood cells [29] Blood cell no synthesis in response to exercise [30] Effects of 24h ultra-marathon on biochemical and hematological parameters Aims Because of the importance of age-linked physiological changes and the effects of physical activity on hematological parameters, this study was conducted to investigate the effects of age and hard endurance workouts on blood cell count and erythrocyte indices. Materials & Methods In this interventional study 87 male volunteers were studied in 3 groups including young (n=30), middle (n=30) and old (n=27) age groups in Sarem hospital (Tehran, Iran). Immediately before and after their endurance activity and during recovery period, hemodynamic factors were measured and 3 blood samples were collected for blood cell count and erythrocyte indices. The data were analyzed by one-way analysis of variance (ANOVA) for independent groups and repeated measures ANOVA for related groups using SPSS 16 software. Findings The plasma volume (%) was decreased significantly after hard endurance workouts and increased significantly during recovery period. Endurance activity caused significant increases in all measured factors other than mean cell volume (MCV). However, there were significant decreases in all studied factors after recovery, except MCV, mean cell hemoglobin (MCH) and mean cell hemoglobin concentration (MCHC). There was no significant difference in responses of hematological factors to the endurance activity and recovery period between different age groups. Conclusion Age does not affect the responses of hematological factors to the hard endurance workouts and subsequent recovery period.bone marrow is fractal. A B S T R A C T A R T I C L E I N F O

Effect of Age and Stress Due to Physical Activity on Blood Cell Count and Red Blood Cell Indices