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Malgorzata Kloc1,2,3*, Rafik Mark Ghobrial1,2, Jacek Z. Kubiak4,5* 1The Houston Methodist Research Institute, Houston, Texas, USA 2The Houston Methodist Hospital, Department of Surgery, Houston, Texas, USA 3The University of Texas, M.D. Anderson Cancer Center, Department of Genetics, Houston Texas, USA 4Department of Regenerative Medicine and Cell Biology, Military Institute of Hygiene and Epidemiology (WIHE), Warsaw, Poland 5UnivRennes, UMR 6290, CNRS, Institute of Genetics and Development of Rennes, Cell Cycle Group, Faculty of Medicine, Rennes, France

Commentary: Trained immunity and beyond: the not-yet lost chance to win with COVID-19