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Despite the different pathways of embryonic development, kidneys and ears share similar mechanisms that can influence both organogenesis1–3. Alport syndrome (sAlport), for example, is known for its phenotype of renal, auditory and ocular involvement4 and affects 1/10.000 individuals. The pathophysiology of this disease lay on a genetic defect in type IV collagen synthesis that interferes with the glomerular filtration barrier4 and degenerates cochlear vascular stria5.

A Careful Interpretation of the Audiometry may contribute to the Diagnosis of Alport Syndrome: A Pilot Study