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The  article  presents  the  results  of  viral  infections  monitoring  in  children  at  different  times  after  renal transplantation and experience of their use in treatment of post-transplant complications. This study presents the results of virological investigation of relevant agents of viral infections (CMV, EBV, HSV 1, 2 tons, HHV 6, HHV 7, VZV, ADV, BKV and JCV). The frequency of  identifying the viral  infections  in blood in  the early postoperative period (the first 3 months after transplantation) was 20.0 %, in the late postoperative period – 8.0 %, in the case of graft dysfunction – 21.4 %. According to the results of PCR tests of urine, BK and / or JC viruses were identified in 40.0 % of  recipients  in  the  early  postoperative  period  and  in  47.1 % of  recipients  in  the  late  postoperative  period. The  dominant pathogens were polyomaviruses, BKV  (22.9 %) prevailed  in  the  early postoperative period,  and  JCV  (36.8 %)  in  the  late postoperative period. There are the examples of treatment of acute transplant rejection combined with HHV 6 viremia and graft dysfunction combined with a  long-term persistence of BKV  infection. The use of vanganciclovir  in  the first case and  the  replacement mycophenolate mofetil (MMF) by azathioprine in the second one allowed stabilizing the function of the transplanted organ.

Infectious status of children after renal transplantation and experience of etiotropic treatment of viral complications