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Abstrak Metabolit sekunder merupakan senyawa yang digunakan untuk menunjang kehidupan organisme, akan tetapi tidak vital dan memiliki aktifitas dibidang farmakologi dan biologi. Mangrove jenis E. agallocha memiliki banyak manfaat yang berhubungan dengan bidang farmakologi seperti antibakteri, antijamur dan antioksidan. Hal ini disebabkan karena memiliki senyawa metabolit sekunder. Tujuan dari penelitian ini adalah untuk mengetahui jenis senyawa bioaktif yang dimiliki oleh daun mangrove jenis E. agallocha setelah mengalami proses perebusan. Penelitian ini dilaksanakan pada bulan Maret sampai April 2018. Pengambilan sampel dilakukan secara purposif sampling. Sampel daun mangrove jenis E. agallocha dibagi menjadi dua, yaitu sampel kering (daun E. agallocha dikeringkan menggunakan oven pada suhu 45 0 C) dan sampel basah (daun E. agallocha direbus sampai mendidih). Skrining fitokimia dilakukan terhadap kedua sampel daun mangrove jenis E. agallocha . Hasil skrining fitokimia menunjukkan bahwa terdapat perubahan kandungan senyawa bioaktifnya. Senyawa bioaktif sampel kering yaitu alkaloid, flavonoid, tanin dan saponin, sedangkan senyawa bioaktif pada sampel basah yaitu alkaloid dan tannin. Kata kunci: Excoecaria agallocha; fitokimia; perebusan Abstract Secondary metabolites are compounds that are used to support organism life but are not vital and have activities in the field of pharmacology and biology. E. agallocha mangroves have many benefits related to pharmacology such as antibacterial, antifungal and antioxidant. This is due to having secondary metabolites. The purpose of this study was to determine the types of bioactive compounds possessed by E. agallocha mangrove leaves after undergoing a boiling process. This research was conducted from March to April 2018. Sampling was conducted purposively. Samples of E. agallocha mangrove leaves were divided into two, namely dry samples ( E. agallocha leaves were dried using an oven at 45 0C) and wet samples ( E. agallocha leaves boiled until boiling). Phytochemical screening was carried out on both samples of E. agallocha mangrove leaves. Phytochemical screening results showed that there was a change in the content of the bioactive compounds. Dry sample bioactive compounds are alkaloids, flavonoids, tannins, and saponins, while bioactive compounds in wet samples are alkaloids and tannins. Keywords: Excoecaria agallocha; phytochemical; boiling

PENGARUH METODE PEREBUSAN TERHADAP UJI FITOKIMIA DAUN MANGROVE Excoecaria agallocha