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The Hippocratea excelsa Kunth (cancerine) plant is widely used for its antimicrobial properties in infectious processes in traditional Mexican medicine; however, there are few scientific papers to support it. Therefore, the objective of this work was to evaluate the antibacterial effect of the ethanol extract of Hippocratea excelsa Kunth to provide evidence about this effect. Methods: The antimicrobial-disk diffusion test, (Kirby Bauer), and a preliminary qualitative phytochemical-phytochemical test were performed. Results: The ethanol extract of cancerine at a dose of 3000mg managed to moderately inhibit the growth of Staphylococcus aureus, Streptococcus pyogenes and Staphylococcus epidermidis, with inhibition halos of 4.5mm, 2.6mm and 2.8mm respectively. In the phytochemical test were found in the ethanol extract: alkaloids, quinones, coumarins, saponins, resins, phenols, tannins, flavonoids and bitter principles. Discussion: The antibacterial activity of some plants has been attributed to the presence of various compounds, including alkaloids, simple phenols, tannins, and flavones; Hippocratea excelsa Kunth presents this type of metabolites, however, the antimicrobial effect was not very significant, compared with the control (commercial) antibiogram. The metabolites found in the ethanol extract of the bark of Hippocratea excelsa Kunth matches with the phytochemical studies of the compounds present in the genus, reported by other research.

Tamizaje fitoquímico preliminar y actividad Antimicrobiana in vitro del extracto etanólico de la corteza de Hippocratea excelsa Kunth (Cancerina)