English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

As dwellers in the same house , it seems only logical that psyche and soma would be in terdependen t , that well-being in one would promote health in th e other, and that illness in one would soon become manifest in its partner. Yet quantifying this intuitive relationship has long been a difficult task. Establishing a mechan ism for d isease-heart disease, infectious disease, neoplastic diseasewhich can withstand the scrutiny of experimental rigor, is difficult enough. T o introduce a seemingly not quantifiable entity such as psychology in th e form of stress or anxiety presents such great complexity that for a long time it seemed that the relationship between mind and body would remain a purely speculati ve one. From the time of Galenus, physicians have suspected that certain psych ological factors resulted in a predisposition to cancer. Galenus wrote that "melancholic women were more prone to cancer than those of sanguine temperamen t" (2). In 1853, James Paget, the English surgeon and pathologist, wrote: " T he cases are frequent in which deep anxiety, deferred hope, and disappointment are quickly fo llowed by the growth or increase of cancer. That we can hardly doubt that mental depression is a weighty addition to the other influences th at favor the development of the cancerous constitution" (3). In the last few years there has been a significant attempt to move th e connection between stress and cancer out of the realm of speculation. Proponents of the psychoneuroendocrine model seek to establish a logical continuum from psychological stress to depressed immune response, mediated by neuroendocrine changes occurring in an hypothalamic-pituitary-adrenal pathway (4, 5). In considering the immune surveillance theory of cancer etiology, and th e role of the immune system in suppressing oncogenic viruses, one must also consider the implications of a stress-induced immune deficiency.

The Stress Factor: Exploring the Possibility of a Psychological Component to Cancer