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This paper presents the results of bioinformatic analysis of three polymorphic loci in 170 women who suffer from a combination of uterine fibroids with endometrium hyperplastic processes and in 981 women of the control group without proliferative diseases of pelvic organs. It was found that the combinations of molecular genetic markers С rs673220, А rs4986938 и G rs887912 (ОR=1.70) are risk factors for the development of a combination of endometrial hyperplasia and uterine myoma among women of the Central region of Russia.

Intergenic Interactions and Hyperplastic Diseases of Endo- and Myometrium