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Leishmaniasis is a disease caused by protozoa of the genus Leishmania of which there are currently about 20 pathogenic species to man. The WHO in 2010 recognizes this disease as one of the great neglected pathologies and estimates that around 98 countries in the majority of developing countries have endemicity. According to estimates by WHO at the present time we would have 12 million people infected with 350 million people living in areas at risk of acquiring the infection, registering 2 million new cases annually. In spite of this, these data are not real since in only 33 countries the disease is declared. At the present time, it is considered an emerging disease, fundamentally due to climate change, migrations, resistance to insecticides by its vectors and the difficulty of its elimination from natural reservoirs. The diagnosis is complicated both at the clinical and laboratory level, which is why effective markers of species and leishmania strain are needed to avoid recognized cross-reactions between species and genera of the same family. Superoxide Dismutases (SODs) are the most interesting group responsible for eliminating the Superoxide Ion (O2-) from the middle by its dismutation in Hydrogen Peroxide (H2O2) and molecular oxygen. All the protozoan parasites studied have shown iron-bound SOD activity, which is considered a virulence factor since it allows the parasites to survive the offensive cellular oxidant. The present work aims to show the prevalence of Leishmania in pediatric populations in the State of Querétaro by using these metalloenzymes that have been shown to be highly effective in the serological agnoses of different genera and species of the trypanosomatid family in the Mexican Republic and particularly in the State of Querétaro, there is a shortage of epidemiological data on species distribution.

journal of tropical medicine and health

Coinfection of Leishmania Mexicana and Leishmania Infantum Chagasi in The Pediatric Population of the State of Querétaro’s (Mexico), Using Fesode as an Antigen