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We developed a SARS-CoV-2 test based on the CDC protocol to determine unrecognized transmission among patients without risk factors for COVID-19 infection. Hospitalized patients with negative respiratory virus tests received the SARS-CoV-2 test from March 12-22, 2020. We did not find any unrecognized COVID-19 infections with this method.

Absence of Unrecognized COVID-19 Community Infections in the Greater Chicago Area Using SARS-CoV-2 Reflex Testing, March 2020