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Because daily dosage is difficult to achieve in topical acne therapy, a dispenser was developed to ensure the delivery of a pre-measured amount (0.5 mL) of adapalene 0.1% / benzoyl peroxide 2.5% (adapalene-BPO). This non-interventional study assessed application and convenience of a pump dispenser, treatment adherence, efficacy and safety under daily practice conditions. The included patients (≥ 9 years) with moderate to severe acne received adapalene-BPO in the pump. Assessments were carried out at baseline and after 3 to 12 weeks of treatment. Overall, 1,388 patients were enrolled, and facial acne severity improved in 96.9% of patients. Application was described as easy and time-saving and89.6% of patients used the acne gel regularly. Dysmorphic concerns were reported in 5.6% of acne patients. Adapalene-BPO dispensed from the pump is easy to apply, simplifies acne treatment and leads to good treatment adherence in patients with moderate to severe inflammatory acne.

Impact of a Dispenser in Acne Therapy - “PUMP It” Study with 1,388 Patients