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The use of immunomodulators in fish culture offers a wide range of attractive methods for inducing or modulating protection against diseases. Several promising synthetic drugs and biological response modifiers stimulate or modulate the nonspecific defence mechanisms and specific cellular and humoral immune responses in fish. This article reviews the literature on the influence of biostimulants on the cellular and humoral defence mechanisms in fish, and present the possibility to application of immunostimulants for control of infectious diseases in aquaculture.

Modulation of Nonspecific Defence Mechanisms and Protection Against Diseases in Fish