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Synthetic hypothalamic preparations of GnRH, produced locally, were administered in the cows of Czech Red and White breed and its crosses with Black and White cattle. There was no difference in the results after the use of DIRIGESTRAN inj. Spofa (5 ml and 10 ml, i.e. 200 mug and 400 mug of gonadorelin, respectively) and SUPERGESTRAN inj. Spofa (4 ml, i. e. 100 mug of the analogue with prolonged and stronger biological activity). The results were significantly worse with the use of lower dose of SUPERGESTRAN inj. Spofa (2 ml, i. e. 50 mug). Altogether 23.9% (26.9%) a smaller number of cows were treated successfully (P < 0.01). The average age of the whole group before the treatment was 4.2 years. The average age of the successfully and unsuccessfully treated cows was 3.63 years and 5.50 years, respectively (P < 0.01). No statistically significant differences were found in the red blood counts before and after the treatment. Concerning the white blood count, a significant difference was found between the relative proportion of neutrophil granulocytes with segmented and non-segmented nucleus before and after the treatment (P < 0.05). A highly significant decrease (P < 0.01) in both absolute and relative numbers of lymphocytes occurred after the treatment. The successfully treated animals showed also a significant decrease of the relative percentage of monocytes (P < 0.05).

The Therapy of Ovarian Cysts in Cattle and the Changes in Blood Count During its Course