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Tumors on the epidermis of the trunk in 2 dogs (8-year-old, male Pomeranian dog and 9-year-old, female mongrel dog) were diagnosed as seborrheic keratosis. Histopathogical examination revealed that the epidermis was acanthotic and broad with a proliferation of the basaloid cells, arranged in glandular structures or cords that interconnected or surrounded the irregular keratin-filled cysts. The prominent hyperpigmantation was observed in the basal layer, and there was pigment clumping in the cysts. The histopathologic findings observed in the dogs are consistent with those in the acanthotic variant of seborrheic keratosis in humans.

Seborrheic Keratosis in Two Dogs