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Background: Indonesia is developing countries with phenomenon raises a variety of issues that require resolution for elderly. The government guarantees social welfare that includes the quality of life of the elderly, such as quality of life of the elderly is influenced by biological, psychological and social. This study was aimed to determine the determinant factors onbio-psychosocial with quality of life in elderly. Subjects and Method: This was observational analytic study using control. This was conducted in Laweyan and Banjarsari, Surakarta. A total of 141 subjects were consisted of 47 cases and 94 controlswere selected busing fixed exposure sampling. The independent variable was a chronic disease, the activity daily living (ADL) independence, social interaction, family support, residence, family income, depression and coping mechanism.The dependent variables were quality of life. The data was collected with a questionnaire and analyzed using path analysis. Results: The result showed that respondents with a good quality of life were in the control group (40.4%). Income is directly related to the quality of life of elderly (b= 0.93; 95% CI <0.01 to 1.86; p= 0.048). The residence was indirectly associated to elderly quality of life with depression, and better residence decreased depression (b= -1.34; 95% CI= -2.08 to -0.61; p<0.001), increasing the quality of life of the elderly (b= -1.01; 95% CI= -1.78 to -0.23; p= 0.010). Family support is not related directly with the quality of life of the elderly through residence and depression. The better family support had the better residence (b= 1.30; 95% CI=-0.35 to 2.26; p= 0.007) depression decreased (b= -1.34; 95% CI= -2.08 to -0.61; p= 0.001) so, improves quality of life elderly (b=-1.01; 95% CI=-1.78 to -0.23; p= 0.010). Depression is directly related to the quality of life of the elderly (b= -1.01; 95% CI= -1.78 to -0.23; p= 0.010). Conclusion: Depression, education and income has a direct relationship with the quality of life of the elderly. Residence with the quality of life of the elderly has an indirect relationship through the depression. Family support is not related directly with the quality of life of the elderly through the shelter and depression.

Association of Determinant Factors on Bio-psychosocial with Quality of Life in Elderly