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This experiment aimed to study the relation of body condition score (BCS) with blood metabolites in dairy cow. At 8 weeks before expected parturition, 90 multiparous Friesian dairy cows were divided according to their body condition score into 3 groups: Group1: low body condition score (n=30, BCS≤2.58, thinner cows); Group2: medium body condition score (n=30, BCS≤3.12, medium BCS cows); Group3: high body condition score (n=30, BCS≤4.75, obesity cows). The cows BCS, weight and back fat thickness were recorded at -60, -21, -14, -7, 0, 7, 14 and 60 days related to calving time. Blood samples were taken at the time of BCS measurement for determination of β hydroxy butyrate, non-esterified fatty acid, haptoglobin, glucose, triglyceride, albumin, aspartate aminotransferase, cholesterol, superoxide dismutase and malonaldehyde. The results showed a significant decrease in body condition score, body weight and back fat thickness throughout the experimental period accompanied by an increase in β hydroxy butyrate, malonaldehyde and cholesterol. The correlation analysis showed that changed body condition score positively allied with cow weight (r=0.860, P 0.05) and aspartate aminotransferase (r=-0.361, P<0.01). Concisely, body condition score loss before and after calving may have significant consequences for blood metabolites, oxidative stress and body condition score profile in dairy cows. Key words : BCS; calving; blood metabolites; Friesian cow

INFLUENCE OF BODY CONDITION SCORE ON BLOOD METABOLITES AND OXIDATIVE STRESS IN PRE- AND POST-CALVING OF FRIESIAN DAIRY COWS IN EGYPT