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Atypical benign partial epilepsy (ABPE) is a complicated form of benign epilepsy with centrotemporal spikes (BECTS) [1]. It is characterized by an earlier age of onset, multiple seizure types including epileptic negative myoclonic, atonic, and atypical absence seizures, as well as focal motor seizures [2]. Electroencephalography (EEG) depicts frequent centrotemporal spikes that are activated during sleep, and similar continuous spike and wave during slow wave sleep (CSWS), but it does not fulfil the standard criteria for CSWS [3]. It has recently been suggested that ABPE is a component of the epilepsy-aphasia spectrum that includes some disorders ranging in severity, where BECTS occurs at the mild end of the spectrum and the severe end includes Landau-Kleffner syndrome and epileptic encephalopathy with CSWS [3]. Patients with ABPE usually exhibit normal neurologic and mental functions through the course, and favorable outcomes [2]. Notably however, some patients reportedly experience cognitive decline, language impairment, and motor skill regression [1,4]. This report describes a boy with ABPE who underwent a very active seizure period accompanied by regression of motor skills, speech, and cognitive function, that was ultimately controlled via ethosuximide and prednisolone. A 3-year-old boy was referred to our clinic for evaluation of focal motor seizures characterized Letter to the editor

Atypical Benign Partial Epilepsy of Childhood Treated with Prednisolone and Ethosuximide