English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Esophagus cancer is a common malignant tumor in China, and itsprevalence rate and fatality rate are the highest in the world whoseoccurrence is related to multiple factors, including family heredity,race, gender, region, diet and so on. Esophagus cancer is the diseasewith the most Chinese characteristic. The pathogenesis of esophagusÂ cancer is very complicated, and the epigenetics in the pathogeneticÂ process has become the current research hotspot, and the reversibleÂ feature provides a new direction for the early screening, preventionÂ and treatment of esophagus cancer. DNA methylation is the mostÂ deep epigenetics in the current study, and the pattern of genomeÂ methylation is often abnormal in the cancerization of esophagusÂ cancer. The folate, as the methyl group donor, and B-vitaminsÂ related to one-carbon metabolism, shall directly influence theÂ condition of DNA methylation, give rise to the change of epigenetics,Â affect the occurrence of esophagus cancer. This paper summarizesÂ the relationship among the occurrence of esophagus cancer andÂ folate, several kinds of B-vitamins related to one-carbon metabolism,Â DNA methylation.

Study on the Relationship Between Folate, Dna Methylation and Esophagus Cancer