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The National Institute for Occupational Safety and Health (NIOSH) requests assistance in controlling exposures of workers to nitrous oxide (N2O) during the administration of anesthetic gas in medical, dental, and veterinary operatories. NIOSH concluded in 1977 that exposure to N2O causes decreases in mental performance, audiovisual ability, and manual dexterity [NIOSH 1977b]. A recent study of workers [Rowland et al. 1992] and several experimental animal studies [Corbett et al. 1973; Vieira 1979; Vieira et al. 1980, 1983] indicate that adverse reproductive effects may also result from chronic exposure to N2O.

Request for assistance in controlling exposures to nitrous oxide during anesthetic administration.