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目的探讨单中心近5年326例肾活检患者肾脏疾病流行病学特点、不同年龄段肾脏疾病构成比的特点。方法回顾性分析单中心326例行肾活检者的年龄、病理类型及临床表现等相关资料。结果原发性肾小球疾病占75.12%继发性肾小球疾病占24.85%。原发性肾小球疾病以IgA肾病最多占42.33%其次分别为系膜增生性肾小球肾炎占22.86%和膜性肾病占15.92%继发性肾小球疾病中以狼疮肾炎多见占38.27%其次是糖尿病肾病占23.46%。各年龄段原发性肾小球肾炎和继发性肾小球炎的构成比比较差异有统计学意义P0.001。另外41.03%的膜性肾病患者年龄位于21~41岁微小病变好发于21~41岁而61岁以上患者最常见为LgA肾病。20岁以下最常见的继发性肾小球肾炎为紫癜性肾炎45.45%21-41岁最常见的继发性肾小球肾炎是狼疮性肾炎45.16%。结论原发性和继发性肾小球肾炎构成比均随年龄变化不同年龄肾炎患者构成比各有特点。

326例肾活检临床病理分析