Open AccessIn vitro Antiplasmodial Activity of Methanol Stem Extract of Costus afer Ker Gawl. (Costaceae) and its Residual Aqueous Fraction Against Some Drug-sensitive and Drug-resistant Plasmodium falciparum Strains
Author(s) -
AbdulFatai Jimoh,
Bilkisu Bello Maiha,
Ben A. Chindo,
Janet I. Ejiofor,
Joseph Olorunmola Ehinmidu,
David Awute Atang,
Jonathan Yusuf Azi
Publication year - 2019
Publication title -
tropical journal of natural product research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.127
H-Index - 4
eISSN - 2616-0692
pISSN - 2616-0684
DOI - 10.26538/tjnpr/v3i5.3
Subject(s) - plasmodium falciparum , in vitro , drug , traditional medicine , chemistry , fraction (chemistry) , biology , pharmacology , chromatography , medicine , malaria , biochemistry , immunology
Malaria is one of the most common infectious diseases in tropical and subtropical countries of the world. The disease is caused by a protozoan parasite of the genus Plasmodium and it is transmitted from the blood of an infected person to a healthy human by the bites of a female anopheles mosquito, through blood transmission, organ transplant or via shared use of needles or syringes that are contaminated with blood or congenitally from a mother to her foetus before or during delivery.1,2 Human malaria is caused by five species of Plasmodium namely: Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, Plasmodium malariae and recently in some parts of Southern Asia by
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