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The present study, investigates themethanolicleaves extract of Wattakaka volubilis (Family: Asclepiadaceae) designated as 'the extract' was evaluated for analgesic activity in mice. The analgesic activity was evaluated in mice models. In the acute toxicity study, it was found that the extract was non-toxic up to 1000mg/kg, p. o. The extract (150, 200 and 400 mg/kg, p. o.) was found to possessanalgesic activities in a dose-dependent manner and the effect was comparable with thatproduced by the standard drug, Diclofenac sodium.

kongunadu research journal

ANTI-ANALGESIC ACTIVITY OF METHANOLIC LEAF EXTRACT OF WATTAKAKA VOLUBILIS (LINN. F.) BENTH EX. HOOK F. (ASCLEPIADACEAE) - A RARE AND THREATENED MEDICINAL PLANT