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A 48-year-old African American female with a medical history of hypertension, GERD, asthma, neurosyphilis and status post meningioma resection presented to the emergency department with complaint of headaches and lethargy for two days. The patient had a remarkable past surgical history of 30 days’ post-operative sphenoid meningioma resection with bilateral craniotomy and on-going treatment with penicillin for active syphilis infection with positive RPR and FTA antibodies. Head CT performed secondary to altered mental status demonstrated right frontal intracranial hemorrhage and the patient underwent emergent craniotomy with hematoma evacuation, without noted complication during surgery. CT angiography of the neck and brain was negative for intracerebral aneurysm and arteriovenous malformation. Coagulopathy studies were negative.

Post Meningioma Resection Complicated by Intracranial Hemorrhage in a Neurosyphilis Patient: A Case Report