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Thrombocytopenia is de ined as a platelet count of less than 1.5 lakhs/μL of anticoagulated blood. Platelet clumping is a common laboratory phenomenon resulting in pseudo thrombocytopenia that complicates platelet counts reporting. Some of the important causes are EDTA dependent agglutination and aggregation secondary to platelet activation, improper collection techniques, or delayedmixingwith anticoagulants. Unfortunately, this pseudo thrombocytopenia is notwell detected by the auto analyzers. In tropical countries like India, where dengue and malaria are endemic and important causes of thrombocytopenia, recognizing pseudo thrombocytopenia and minimizing the errors in platelet enumeration becomes vital. In this study, we compared various platelet indices between true thrombocytopenia and pseudo thrombocytopenia cases and found that only MPV is statistically signi icant. Hence, low platelet counts given by the automated hematology analyzer should be veri ied by a well stained peripheral smear and management should not go only by platelet parameters from the automated analyzer. This will prevent unnecessary referrals and platelet transfusions for the patient and thereby improve patient care.

Thrombocytopenia Vs Pseudo thrombocytopenia Will indices help us???