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Ipomoea pestigridis (Linn) (family Convolvulaceae) is commonly known as “Tiger Foot Morning Glory” in English and locally known as ‘Pulichuvadi’ or ‘Pulichuvadu’ in Malayalam. The current study, aerial parts of different concentrates(Pet.ether, ethyl acetate, and methanol) of I.pestigridis, was evaluated for its in-vitro antioxidant potential by nitric oxide activity, total antioxidant activity, iron chelating activity taking ascorbate u0026 Ethylenediamine tetraacetate as the standard correspondingly. An IC50 value was originated that EA concentrates of I.pestigridis  more efficient in nitric oxide activity, total antioxidant activity, Iron chelating capacity compared methanolic u0026 PE concentrates. The ethyl acetate concentrates of I.pestigridis  u0026 ascorbic acid exhibited antioxidant potential possessing IC50 226µg/ml u0026 66µg/ml (Nitric oxide). 185µg/ml u0026 60µg/ml (total antioxidant) , 287µg/ml u0026 65µg/ml (iron-chelating Activity) respectively. The difference in the scavenging potential of the extracts can be due to variation in the percentage of bioactive compounds present in different solvents.  Invitro antioxidant studies obviously show  EA concentrates of I.pestigridis have better antioxidant activity. These results indicate that aerial parts of methanolic concentrate I.pestigridis  could serve as a natural antioxidant, which may be useful in preventing free radical-induced diseases.

Evaluation of in vitro antioxidant activity of different extracts of entire plant of Ipomoea pestigridis Linn