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Since elastase participates not only in elastolysis but also in elastogenesis, it has been regarded as a regulator of elastin metabolism. According to Balo and Banga, the enzyme decreases with the aging of animals and in patients with arteriosclerosis. In this study, the effect of elastase on the elastic tissues of the thoracic aortas of young and old rats was examined using morphological and histochemical techniques. From the findings obtained, the elastic laminae and elastic branches in the thoracic aortas excised from elastase-administered rats did not look parched in contrast to those of control rats. The resistance of the elastic

Effect of Elastase on the Elastic Tissues in the Thoracic Aorta