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Creighton (1896) said that glycogen is of considerable significance in tooth development, ever since a great amount of histochemical research on the distribution of the PAS-positive polysaccharide in the tooth germ has been reported (Horrowitz, 1942 ; Grauman, 1952 ; Dalcq and Mulnard, 1953 ; Sakuma and Oh'ya 1957 ; Dalcq, 1960 ; Pourtois, 1961 ; Ten Cate, 1962 ; Mattiessen, 1963). However, there has been controversy as to its localization in the tooth germ. On the other hand, the relation with the morphogenesis and the metabolism in the early tooth development is poorly understood, little is known about whether the developmental metabolism is almost the same in the upper and the lower tooth germs and whether the discrepancy in metabolism is recognized by the difference in the position of the individual tooth germ on the buccal side or on the lingual side and at the medial, median or distal parts. The purpose of the present paper is to determine the threedimensional distribution of the PAS-positive substances and the PAS positive areas in the upper and lower individual tooth germ.

Discrepancy of Distribution of PAS-positive Substances by Difference in Position of Early Individual Tooth Germ