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Although the central nervous system which participates in the respiratory movements has been considered to be localized over the considerably large areas of the brain, those which take direct part in the respiratory centers of the automatic rhythmicity, the so-called primary respiratory centers, are in the pons and medulla oblongata, out of the brain stem, especially in the formatio reticularis. Researches have been conducted on this subject by many scholars such as Pitts (1939) and others'"). Various investigations have been reported concering the role played by the cerebral cortex (S m i t h 1936 and others"-") and the mesencephalon (L um s d en 1923 and others"""-") on the primary center. Further, since Hering and Breuer (1868)10), numerous studies have been taken up on the influences of the peripheral nervous system, the main constituent of which is the vagal nerve, upon the central nervous system. Since 1960 the present authors have been pursuing researches on the autonomic centers, centering the attention upon the blood pressure and the respiratory movements, covering the whole range of the brain stem of the cat from the hypothalamus to the medulla, oblongata. A part of our results has already been published") concerning the changes of the blood pressure and the respiratory movements caused by electrical stimulation of hypothalamus in cats. The parts played by the hypothalamus of diencephalon upon the primary respiratory centers have been observed in more cases since then, about which comparatively fewer researches have been reported the following will be the description on considerably clear-cut observations obtained in regard to the acceleratory and inhibitory responses.

On the Changes in Respiratory Movements Caused by Electrical Stimulation of Hypothalamus in the Cat