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What was the project about? Comparative effectiveness research compares two or more treatments to see which one works best for which patients. But patient traits, such as age or income, may affect patients’ treatment choices. These traits may also affect patients’ responses to treatments. As a result, researchers may have trouble telling whether a patient’s traits, the treatment, or a mix of the two affected how well a treatment worked.

Creating and Testing Methods to Estimate Treatment Effect in Observational Studies with Three or More Treatments