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An infrared free-electron laser (IR-FEL) is operated as a pulsed and linearly polarized laser with tunable wavelengths within infrared region. IR-FEL can alter molecular structures of almost kinds of chemical substances which have vibration absorption bands in infrared region. We show here efficient dissociation of amyloid fibrils causing amyloidosis by using IR-FEL tuned to amide band.

Photo-Dissociation of Amyloid Fibrils by using IR Free Electron Laser