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Optical coherence tomography in patients with refractive errors. Part 2: Optic disc parameters A.A. Shpak, M.V. Korobkova The S . Fyodorov Eye Microsurger y Federal State Inst i tut ion , Moscow Purpose. To develop an available affordable method to evaluate an influence of the optical system of long or short eyes on the disc area (DA) and the rim area (RA), measured by the optical coherence tomography (OCT). Material and methods. The study involved 46 patients (46 eyes) aged 18 to 40 years, with moderate and high myopia and the best corrected visual acuity (BCVA) not lower than 0.8. There were also examined 53 healthy persons with emmetropia of the same sex and age (the comparison group) and 117 healthy emmetropic individuals aged 41-84 years (the group «over 40 years old»). The OCT was performed using the Cirrus HDOCT device (Carl Zeiss Meditec). Results. To correct the area of object, measured using the OCT in the ocular fundus, the known calculation formulas were modified and adopted to the emmetropic eye with the axial length 23.5mm. The DA and RA normative data were defined for such eyes. In patients with myopia, the RA (1.31±0.25mm2) was significantly lower in relation to the comparison group (1.46±0.22mm2; P<0.002), but became significantly higher when modified by the suggested correction method (1.71±0.36mm2; P<0.000). Prior to a correction, the DA (1.58±0.33mm2) was significantly less than in the comparison group (2.00±0.36mm2; P<0.000), but practically did not differ from it after a correction (2.07±0.47mm2). Before a correction the DA and RA did not correlate with the axial length of the eye, while after a correction the significant direct correlation was revealed: r=0.39 (P=0.007) and 0.35 (P=0.016), respectively. Conclusion. The OCT devices by most manufacturers do not take into account the effect of refractive errors, especially of high degree, on the quantitative optic disc parameters. For a correct interpretation of the measurements of the DA, RA areas and other objects in the ocular fundus in these patients, the existing methods of calculation were improved and implemented in the original formulas and tables.