English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Wound healing is a dynamic phenomenon that results in the restoration of anatomic continuity and function on which canbe delayed by pathogenic bacteria. This research was designed to explore the antimicrobial efficacy of Tillandsiausneoides against skin infections in wound healing. Physical and chemical evaluations were done through phytochemicalscreening and thin layer chromatography. The effect of methanolic, ethanolic and aqueous extracts of Tillandsiausneoides against pathogenic bacteria were evaluated on antimicrobial activities using disc diffusion and broth dilutionsusceptibility assay. The excision bioassay analysis was used in examining the wound healing process in mice. The resultof the qualitative phytochemical screening showed the presence of flavonoids and alkaloids. Thin layer chromatographyrevealed a high Rf value for flavonoids (0.75mm) and alkaloids (0.60mm). The antibacterial assay showed a high zone ofinhibition (ZI) for both methanolic extract (>23mm, >22mm and >20mm) and ethanolic extract (>22mm, >22mm and>17mm) for P.aeruginosa, S.aureus and S.epidermis respectively. Resistance against aqueous extract was observed basedon the lowest zone of inhibition ( less than 4mm). Gentamicin was used as the positive control (>28mm) and DMSO as thenegative control. The minimum inhibitory concentration and minimum bactericidal concentration results confirmed thatmethanolic and ethanolic extracts restrained the growth of tested bacteria in the range of 125 to 500mg/mL and showedbactericidal efficacy. Wound healing assay indicated that methanolic extract had a higher potency of wound closure (12days; less than 1mm) compared to ethanolic and aqueous extracts (13days; >1.5mm and 13days: >1.8mm respectively).Povidone-Iodine was used as the gold standard (15days; less than 2mm) in the study. In conclusion, methanolic extract of T.usneoides has a great potential with regard to its antimicrobial and wound healing activity to be developed as a noveldrug in the future.

In Vitro Antibacterial Activity of Spanish Moss (Tillandsia usneoides) Crude Extract Against Skin Infection in Wound Healing