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Background. Psoriasis is a chronic skin disorder that impairs patients health-related quality of life. It is associated with patients need in specialized medical care and with essential medical costs. Psoriasis may be the reason for temporary or permanent disability. Patient registries are important sources of epidemiological and clinical data on patients with psoriasis and medical care provided.&#x0D;Aims. To describe demographic characteristics, characteristics of the disease, prevalence of concomitant and past diseases in adult (18 years and older) patients with moderate and severe psoriasis included in the patient registry of the Russian Society of Dermatovenereologists and Cosmetologists.&#x0D;Materials and methods. The data of 3,268 patients with psoriasis aged 18 years and older were analyzed as of inclusion in the registry. Data lock point was June 3, 2021. Descriptive statistics methods were applied in data analysis.&#x0D;Results. The mean ( SD) age of adult patients at inclusion in the registry was 46.1  14.4 years. Male patients accounted for 60.5%. The mean age of onset of psoriasis is 31.1  16.1 years. Most of the patients (89.5%) have psoriasis vulgaris. The mean body surface area at inclusion was 43.3%  24.7%. 28.9% of patients had psoriatic arthritis at inclusion in the registry.&#x0D;A high prevalence of cardiovascular diseases was revealed: arterial hypertension  28.5%, coronary heart disease  5.4%, myocardial infarction and acute cerebrovascular accident  0.9% each.&#x0D;More than half of patients are pre-obese or obese according to the WHO body mass index classification. 2.2% of patients have impaired glucose tolerance, 6.7% of patients have type 2 diabetes mellitus. 3.8% of patients have diseases or dysfunction of the thyroid gland.&#x0D;The prevalence of diseases of the digestive system is high: any disease of the esophagus, stomach and duodenum was noted in 10.2% of patients, any disease of the liver, gallbladder, biliary tract and pancreas  in 11.8% of patients.&#x0D;The prevalence of viral hepatitis C among patients with psoriasis was 2.6%.&#x0D;Conclusions. The prevalence of comorbidities is high among Russian patients with moderate and severe psoriasis.

Epidemiology of psoriasis in the Russian Federation according to the patient registry