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Aim. This study was designed for the morphological assessment of the state of tooth pulp tissues after simulated acute 29 Kuanskij nachnyj m edinskij vstnik 218; 25 5) trauma under the influence of the developed dental treatment pad and three analogues in the treatment of deep caries and acute focal pulpitis. Materials and methods. In the course of the experiment the study was conducted on white laboratory rats. The cavities on the molar chewing surface of the upper jaw were formed by spherical burs. The experimentally formed lesions of the surface layer of the pulp were treated using the developed dental preparation and three analogues. Laboratory animals were withdrawn from the experiment on days 3, 7 and 30. Animal teeth were put in a 10% neutral formalin solution, decalcified for 3 days and then put into a mounting medium. The slices obtained had a thickness of 5-15 μm. Results. In the course of the experimental study we detected the activation of reactive and compensatory processes in the tooth pulp tissue with the preservation of its viability by using the developed dental therapeutic preparation and the Biodentin as a comparison preparation on the 30th day of the experiment. Histologically, these changes were expressed in an increase in the level of metabolic processes and in the activation of cellular elements of the tooth pulp tissue on the 30th day of the experiment. Conclusion. As a result of an experimental study of the developed dental therapeutic preparation for the treatment of deep caries and acute focal pulpitis, there was established a specific and multifunctional property in preventing and prophylaxis of the inflammation development and enhancing the protective properties of the pulp tissue under the influence of this preparation. Morphological evaluation of the application of the developed dental treatment pad showed a rapid arrest of the inflammatory response of the pulp tissue within 30 days and the normalization of the main components of the tooth pulp. Developed during the conducted experimental research dental therapeutic preparation confirmed its stated properties, in particular, anti-inflammatory, antiseptic, analgesic, moreover, it is not inferior in its properties to the drugs presented in the course of the experimental study.

MORPHOLOGICAL SUBSTANTIATION OF APPLICATION OF THE DEVELOPED STOMATOLOGIC MEDICAL PREPARATION BY THE BIOLOGICAL METHOD OF TREATINMENT OF THE PULPITIS