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We investigated the effect of cultured human intestinal microflora on several mycotoxins, ochratoxin A (OCTA), patulin, zearalenone, citrinin, aflatoxin B1 and fumonisin B1, B2. Human intestinal microflora derived from a Japanese health adult was cultured using continuous flow culture system we had developed previously. We examined the recoveries of seven mycotoxins after incubation with human intestinal microflora for 8 hr. As a result, zearalenone, citrinin, and aflatoxin B1 were not degraded by human intestinal microflora for 8 hr incubation. It was, however, suggested that OCTA and fumonisin B1, B2 might he partially degraded by human intestinal microflora.

The degradation of several mycotoxins by human intestinal microflora cultured by continuous flow culture system