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Objectives: Nearly 65–70% of pregnant women in the United States (U.S.) experience one or more stressful life events (SLEs), which can lead to adverse maternal and/or fetal outcomes. This study aimed to identify groups of women, with similar patterns of antenatal SLE experiences, and to examine their socio-demographic correlates. Methods: Data from 2009–11 Pregnancy Risk Assessment Monitoring System (PRAMS) were used and latent class analysis (LCA) performed (N=115,704), to identify unobserved class membership. The relative likelihood of membership in each latent class was explored using mutinomial logistic regression. Results: A three-class model was most appropriate, with majority (64%) in low-stress class. The illness/death related-stress class (13%) had a high prevalence of illness (77%) and death (63%) of a family member/someone close, while those in the multiple-stress (22%) class endorsed most other SLEs. Unmarried and lowest-poverty women were respectively more (adjusted odds ratio [aOR]: 2.46; 95% confidence interval [CI]: 2.20, 2.74) and less likely (aOR: 0.13; 95% CI: 0.10, 0.16) to be in the multiple-stress class. Severe pregnancy-associated nausea/vomiting, preterm labor, and postpartum depression had a markedly higher prevalence in the group experiencing multiple-stress, followed by illness/death and low-stress classes. Conclusions: That 1 out of every 5 and 1 out of every 8 women were in the multipleand illness/death relatedstress classes respectively suggest that SLEs are common among pregnant women. The

Antenatal Stressful Life Events and Postpartum Depression in the United States: the Role of Women’s Socioeconomic Status at the State Level