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Effects of salinomycin (SL) on the growth of young calves reared from 3 to 25 weeks of age and on their blood and ruminal characteristics were investigated using 10 Holstein male calves. Calves were offered limited amounts of concentrate with 0 or 15ppm SL and hay ad libitum from 1 week of age. SLnontreated calves were fed a calf starter mixed with 50ppm chlorotetracycline instead of SL until 13 weeks of age. SL feeding tended to stimulate not only body weight gain but feed (concentrate) intake, and a resultant improvement of feed conversion was 6.3% with no statistical significance. Blood serum calcium, magnesium, phosphate, cholesterol, glucose, proteins and urea-N levels in both control and SL fed groups were within a normal range and were not affected by SL. When SL was fed ruminal VFA composition in calves after weaning except for 17 and 21 weeks of age tended to be altered toward more propionate less acetate and butyrate, though pH and total VFA level remained unchanged. Throughout the experiment SL-fed calves tended to have lower concentrations of ruminal ammonia N and α-amino N. When SL was given from 1 week of age and the development of ruminal papillae was examined at 7 weeks of age, there was found no apparent influence on the growth of ruminal papillae judging from their length, color and shape. The digestion trial conducted at 26 weeks of age showed that dietary SL would prolong mean retention time of digesta and depress NDF and ADF digestibilities. Jpn. J. Zootech. Sci., 59 (7): 643-652, 1988

Effect of Salinomycin on Growing Calves Reared from 3 to 25 Weeks of Age