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The Epstein Barr virus (EBV) is a common infectious agent in the pediatric population, and one responsible for infections that are not symptomatic and are self-limiting. However, in some situations, the virus presents with atypical manifestations and severe outcomes. Therefore, we report one case of hepatitis and another case of hemophagocytic lymphohistiocytosis, both related to EBV infection, accompanied at the Pediatric Unit of the Santa Casa Hospital of the Santa Casa Group of Belo Horizonte, followed by a literature review on the topics, in order to alert pediatricians about the importance of early recognition of these clinical conditions.

The hidden face of mononucleosis: report of two atypical cases involving this clinical syndrome